LDE225

Pre-clinicalCompleted
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23
Hype Score

Development Stage

1
Pre-clinical
2
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Basal Cell Carcinoma

Conditions

Basal Cell Carcinoma

Trial Timeline

Feb 1, 2012 โ†’ Aug 1, 2013

About LDE225

LDE225 is a pre-clinical stage product being developed by Novartis for Basal Cell Carcinoma. The current trial status is completed. This product is registered under clinical trial identifier NCT01529450. Target conditions include Basal Cell Carcinoma.

Hype Score Breakdown

Clinical
5
Activity
2
Company
10
Novelty
2
Community
1

Clinical Trials (11)

NCT IDPhaseStatus
NCT02195973Phase 1Completed
NCT02151864Phase 1Completed
NCT02086513Phase 1Terminated
NCT02002689Phase 2Terminated
NCT01826214Phase 2Completed
NCT01764776Phase 1Completed
NCT01529450Pre-clinicalCompleted
NCT01327053Phase 2Completed
NCT01125800Phase 1/2Completed
NCT01208831Phase 1Completed
NCT00880308Phase 1Completed

Competing Products

20 competing products in Basal Cell Carcinoma

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Part 1: VP-315 3 Day Dosing/Week + Part 2: VP-315 3 Day Dosing/Week - Loading Dose + Part 2: VP-315 3 Day Dosing/Week - No Loading Dose + Part 2: VP-315 2 Day Dosing/Week - Split Dose + Part 2: VP-315 3 Day Dosing/Week - Split DoseVerrica PharmaceuticalsPhase 2
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sonidegibSun PharmaceuticalPre-clinical
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Sonidegib Phosphate CapsulesSun PharmaceuticalApproved
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VismodegibSun PharmaceuticalPhase 2
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Cemiplimab Injection [Libtayo]Sun PharmaceuticalPhase 2
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Natural Killer Cell Therapy + Universal Donor Expanded TGF-beta-imprinted NK CellsJohnson & JohnsonPhase 1
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ABBV-8E12AbbViePre-clinical
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Pembrolizumab + VismodegibMerckPhase 1/2
41
LDE225B + VehicleNovartisPhase 2/3
65
verteporfin PDTNovartisPhase 3
77
Vehicle + LDE225 0.25% + LDE225 0.75%NovartisPhase 2
52
LDE225NovartisPhase 2
52
LDE225 + PlaceboNovartisPhase 2
52
Buparlisib + SonidegibNovartisPhase 2
52
LDE225 0.75% + VehicleNovartisPhase 2
52
VismodegibRochePre-clinical
23
ERIVEDGERochePhase 2
52
Placebo + VismodegibRochePhase 2
52
vismodegibRochePhase 2
52