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KHK4951 + Aflibercept Injection

Phase 2Active
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Interest: 39/100
39
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Neovascular Age-Related Macular Degeneration (nAMD)

Conditions

Neovascular Age-Related Macular Degeneration (nAMD)

Trial Timeline

Jan 31, 2024 → Sep 30, 2026

NCT ID
NCT06116890

About KHK4951 + Aflibercept Injection

KHK4951 + Aflibercept Injection is a phase 2 stage product being developed by Kyowa Kirin for Neovascular Age-Related Macular Degeneration (nAMD). The current trial status is active. This product is registered under clinical trial identifier NCT06116890. Target conditions include Neovascular Age-Related Macular Degeneration (nAMD).

What happened to similar drugs?

18 of 20 similar drugs in Neovascular Age-Related Macular Degeneration (nAMD) were approved

Approved (18) Terminated (3) Active (2)
✅ranibizumabNovartisApproved
✅RanibizumabNovartisApproved
✅Intraviteal Ranibizumab 0.5mgNovartisApproved
✅RanibizumabNovartisApproved
✅RanibizumabNovartisApproved
✅RanibizumabNovartisApproved
✅BrolucizumabNovartisApproved

Hype Score Breakdown

Clinical
12
Activity
12
Company
15
Novelty
0
Community
0

Clinical Trials (2)

NCT IDPhaseStatus
NCT06116890Phase 2Active
NCT06116916Phase 2Active

Competing Products

20 competing products in Neovascular Age-Related Macular Degeneration (nAMD)

See all competitors
ProductCompanyStageHype Score
CLS-AX + Anti-VEGFClearside BiomedicalPhase 1/2
22
CLS-AX + AfliberceptClearside BiomedicalPhase 2
25
Eylea + ALT-L9AlteogenPhase 1
29
UBX1325 injection 50 μL + EYLEA® (aflibercept) Injection 2 mg (0.05mL)Unity BiotechnologyPhase 2
25
DS-7080a + RanibizumabDaiichi SankyoPhase 1
29
Avacincaptad PegolAstellas PharmaPhase 1
29
Avacincaptad Pegol + Avastin + Lucentis + EyleaAstellas PharmaPhase 2
27
Avacincaptad Pegol + LucentisAstellas PharmaPhase 2
35
Surabgene Lomparvovec (ABBV-RGX-314) + Ranibizumab ControlAbbViePhase 3
47
Ranibizumab + Local Steroid + Topical SteroidAbbViePhase 2
39
LucentisNovartisPre-clinical
26
ranibizumabNovartisPhase 3
40
BrolucizumabNovartisPre-clinical
18
ranibizumabNovartisApproved
43
brolucizumab + ranibizumab + afliberceptNovartisPre-clinical
26
BeovuNovartisPre-clinical
26
RanibizumabNovartisPhase 3
40
RanibizumabNovartisApproved
43
Intraviteal Ranibizumab 0.5mgNovartisApproved
43
RanibizumabNovartisApproved
43