BiotechTube

Ibrutinib + Venetoclax

Phase 2Completed
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Interest: 35/100
35
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Mantle Cell Lymphoma (MCL)

Conditions

Mantle Cell Lymphoma (MCL)

Trial Timeline

Sep 23, 2020 → May 28, 2025

NCT ID
NCT04477486

About Ibrutinib + Venetoclax

Ibrutinib + Venetoclax is a phase 2 stage product being developed by AbbVie for Mantle Cell Lymphoma (MCL). The current trial status is completed. This product is registered under clinical trial identifier NCT04477486. Target conditions include Mantle Cell Lymphoma (MCL).

What happened to similar drugs?

1 of 6 similar drugs in Mantle Cell Lymphoma (MCL) were approved

Approved (1) Terminated (1) Active (4)
✅Acalabrutinib capsuleAstraZenecaApproved
🔄Pirtobrutinib + Ibrutinib + Acalabrutinib + ZanubrutinibEli LillyPhase 3
🔄Rituximab 375 mg/m^2 + Cyclophosphamide 750 mg/m^2 + Doxorubicin 50 mg/m^2 + VELCADE 1.3 mg/m^2 + Prednisone 100 mg/m^2 + Vincristine 1.4 mg/m^2Johnson & JohnsonPhase 3
🔄Acalabrutinib + Bendamustine + Rituximab + PlaceboAstraZenecaPhase 3
🔄Sonrotoclax + Zanubrutinib + PlaceboBeOne MedicinesPhase 3
❌parsaclisib + rituximab + bendamustine + PlaceboIncytePhase 3

Hype Score Breakdown

Clinical
12
Activity
8
Company
15
Novelty
0
Community
0

Clinical Trials (3)

NCT IDPhaseStatus
NCT04477486Phase 2Completed
NCT04273139Phase 2Active
NCT02956382Phase 1/2Completed

Competing Products

20 competing products in Mantle Cell Lymphoma (MCL)

See all competitors
ProductCompanyStageHype Score
Pirtobrutinib + Brexucabtagene AutoleucelEli LillyPhase 2
42
Obinutuzumab + Glofitamab + PirtobrutinibEli LillyPhase 2
42
enzastaurinEli LillyPhase 2
35
AbemaciclibEli LillyPhase 2
35
Pirtobrutinib + Ibrutinib + Acalabrutinib + ZanubrutinibEli LillyPhase 3
44
Pirtobrutinib + Rituximab + VenetoclaxEli LillyPhase 2
42
Pirtobrutinib and rituximabEli LillyPhase 2
42
gemcitabine + mitoxantrone + rituximabEli LillyPhase 2
35
Rituximab 375 mg/m^2 + Cyclophosphamide 750 mg/m^2 + Doxorubicin 50 mg/m^2 + VELCADE 1.3 mg/m^2 + Prednisone 100 mg/m^2 + Vincristine 1.4 mg/m^2Johnson & JohnsonPhase 3
40
VenetoclaxAbbViePhase 2
35
ABT-199 and Ibrutinib CombinationAbbViePhase 1
29
Venetoclax Oral Tablet [Venclexta]AbbViePhase 2
27
Acalabrutinib capsuleAstraZenecaApproved
43
Acalabrutinib in combination with BR + Acalabrutinib in combination with VRAstraZenecaPhase 1
33
Acalabrutinib + Venetoclax + ObinutuzumabAstraZenecaPhase 1/2
39
Acalabrutinib + R-CHOP standard of care + Acalabrutinib combination with Rituximab + Acalabrutinib monotherapyAstraZenecaPhase 2
42
Acalabrutinib + Venetoclax + RituximabAstraZenecaPhase 2
39
Acalabrutinib + RituximabAstraZenecaPhase 2
42
Acalabrutinib Treatment A + Acalabrutinib Treatment B + Acalabrutinib Treatment C + Acalabrutinib Treatment DAstraZenecaPhase 1
29
Acalabrutinib + Lenalidomide + Rituximab + ObinutuzumabAstraZenecaPhase 2
39