Hydroxyurea

ApprovedTerminated

1 views this week 0 watching💤 Quiet

Interest: 35/100

Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

✓

Phase 2

✓

Phase 3

Approved

Indication / Disease

Polycythemia Vera

Conditions

Polycythemia Vera

Trial Timeline

Jul 28, 2023 → Feb 26, 2026

NCT ID

NCT05853458

About Hydroxyurea

Hydroxyurea is a approved stage product being developed by Novartis for Polycythemia Vera. The current trial status is terminated. This product is registered under clinical trial identifier NCT05853458. Target conditions include Polycythemia Vera.

What happened to similar drugs?

1 of 16 similar drugs in Polycythemia Vera were approved

Approved (1) Terminated (0) Active (15)

🔄Sapablursen + PlaceboOno PharmaceuticalPhase 3

🔄Ruxolitinib + Hydroxycarbamide + Interferon-AlphaNovartisPhase 3

🔄ruxolitinib tabletsNovartisPhase 3

🔄RuxolitinibNovartisPhase 3

🔄Best Available Therapy + RuxolitinibNovartisPhase 3

🔄PEGASYS + Hydroxyurea + AspirinRochePhase 3

🔄Pegylated-Proline-Interferon alpha-2b in a Pre-filled PenPharmaEssentiaPhase 3

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (2)

NCT ID	Phase	Status	Start	Completion	Indication
NCT05285917	Phase 3	Recruiting	Nov 15, 2023	Sep 1, 2027	Sickle Cell Anemia in Children
NCT05853458	Approved	Terminated	Jul 28, 2023	Feb 26, 2026	Polycythemia Vera

Competing Products

20 competing products in Polycythemia Vera

See all competitors

Product	Company	Stage	Hype Score
Sapablursen + Placebo	Ono Pharmaceutical	Phase 3	47
Ruxolitinib + Abemaciclib	Eli Lilly	Phase 1	36
Bomedemstat	Merck	Phase 2	35
Ruxolitinib + Hydroxycarbamide + Interferon-Alpha	Novartis	Phase 3	47
ruxolitinib tablets	Novartis	Phase 3	40
Ruxolitinib	Novartis	Pre-clinical	26
Ruxolitinib	Novartis	Phase 3	40
Ruxolitinib + BAT	Novartis	Phase 2	39
Best Available Therapy + Ruxolitinib	Novartis	Phase 3	40
Smac Mimetic LCL161	Novartis	Phase 2	35
PEGASYS + Aspirin	Roche	Phase 2	35
RG7388 + Pegasys	Roche	Phase 1	29
Idasanutlin	Roche	Phase 2	27
PEGASYS + Hydroxyurea + Aspirin	Roche	Phase 3	40
Ropeginterferon alfa-2b	PharmaEssentia	Phase 2	39
Pegylated-Proline-Interferon alpha-2b in a Pre-filled Pen	PharmaEssentia	Phase 3	40
Pegylated-Proline-interferon alpha-2b + Best available therapy (BAT)	PharmaEssentia	Phase 3	40
Ropeginterferon alfa-2b	PharmaEssentia	Approved	50
P1101 + Low-dose aspirin	PharmaEssentia	Phase 2	35
P1101 (Ropeginterferon alfa-2b)	PharmaEssentia	Phase 3	47