Exa-cel

Phase 3Recruiting
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Interest: 47/100
47
Hype Score

Development Stage

Pre-clinical
Phase 1
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Sickle Cell Disease

Conditions

Sickle Cell Disease

Trial Timeline

Jul 31, 2027 → Dec 31, 2033

About Exa-cel

Exa-cel is a phase 3 stage product being developed by Vertex Pharmaceuticals for Sickle Cell Disease. The current trial status is recruiting. This product is registered under clinical trial identifier NCT05951205. Target conditions include Sickle Cell Disease.

What happened to similar drugs?

3 of 20 similar drugs in Sickle Cell Disease were approved

Approved (3) Terminated (10) Active (8)
Prasugrel + PlaceboDaiichi SankyoPhase 3
ICA-17043Johnson & JohnsonPhase 3
Ticagrelor + PlaceboAstraZenecaPhase 3
Brilinta + PlaceboAstraZenecaPhase 3
🔄Crizanlizumab + PlaceboNovartisPhase 3
CrizanlizumabNovartisApproved
🔄HydroxyureaNovartisPhase 3

Hype Score Breakdown

Clinical
17
Activity
15
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT05951205Phase 3Recruiting

Competing Products

20 competing products in Sickle Cell Disease

See all competitors
ProductCompanyStageHype Score
Prasugrel + PlaceboDaiichi SankyoPhase 3
32
PrasugrelDaiichi SankyoPhase 1
29
Prasugrel + PlaceboDaiichi SankyoPhase 2
35
PrasugrelDaiichi SankyoPhase 2
35
LexiscanAstellas PharmaPhase 1
29
Placebo + DalteparinEisaiPhase 2
35
tadalafil + placeboEli LillyPhase 2
27
Prasugrel (clinical formulation) + Prasugrel (Orally Disintegrating Tablet [ODT])Eli LillyPhase 1
29
Lidocaine Iv + PlaceboJohnson & JohnsonPhase 2
31
ICA-17043Johnson & JohnsonPhase 3
32
TicagrelorAstraZenecaPhase 1
29
Ticagrelor granule + Ticagrelor pediatric tablets + Ticagrelor pediatric tablets suspended in water + Ticagrelor immediate release (IR) tablets (Commercial tablet)AstraZenecaPhase 1
29
Ticagrelor + PlaceboAstraZenecaPhase 2
35
Ticagrelor + PlaceboAstraZenecaPhase 3
32
Brilinta + PlaceboAstraZenecaPhase 3
32
Ticagrelor Dose 1a + Dose 2a + Ticagrelor Dose 1b + Dose 2bAstraZenecaPhase 2
35
vorinostatMerckPhase 2
27
Crizanlizumab + PlaceboNovartisPhase 3
47
Crizanlizuamb + Standard of CareNovartisPhase 2
35
CrizanlizumabNovartisApproved
50