Conditioning Regimen A + Conditioning Regimen B + Conditioning Regimen C + Conditioning Regimen D + Conditioning Regimen E + PTCy (50 mg/kg D3, D4) + PTCy (25 mg/kg D3, D4) + Post-transplant Tacrolimus + Post-transplant Mycophenolate mofetil + Post-transplant Abatacept + Post-transplant Ruxolitinib + Supportive Care: Growth Factors + Supportive Care: Seizure prophylaxis + Supportive Care: Prophylaxis against infections

Phase 2Recruiting
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Interest: 39/100
39
Hype Score

Development Stage

Pre-clinical
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

AML (Acute Myelogenous Leukemia)

Conditions

AML (Acute Myelogenous Leukemia), Acute Lymphoid Leukemia (ALL), Acute Leukemia (Category), MDS (Myelodysplastic Syndrome), CML (Chronic Myelogenous Leukemia), CLL (Chronic Lymphocytic Leukemia), Prolymphocyctic Leukemia, Chronic Myelomonocytic Leukemia (CMML), Myeloproliferative Neoplasm (MPN), Lymphoma, Myelofibrosis

Trial Timeline

Jul 25, 2025 → Jun 1, 2028

About Conditioning Regimen A + Conditioning Regimen B + Conditioning Regimen C + Conditioning Regimen D + Conditioning Regimen E + PTCy (50 mg/kg D3, D4) + PTCy (25 mg/kg D3, D4) + Post-transplant Tacrolimus + Post-transplant Mycophenolate mofetil + Post-transplant Abatacept + Post-transplant Ruxolitinib + Supportive Care: Growth Factors + Supportive Care: Seizure prophylaxis + Supportive Care: Prophylaxis against infections

Conditioning Regimen A + Conditioning Regimen B + Conditioning Regimen C + Conditioning Regimen D + Conditioning Regimen E + PTCy (50 mg/kg D3, D4) + PTCy (25 mg/kg D3, D4) + Post-transplant Tacrolimus + Post-transplant Mycophenolate mofetil + Post-transplant Abatacept + Post-transplant Ruxolitinib + Supportive Care: Growth Factors + Supportive Care: Seizure prophylaxis + Supportive Care: Prophylaxis against infections is a phase 2 stage product being developed by Incyte for AML (Acute Myelogenous Leukemia). The current trial status is recruiting. This product is registered under clinical trial identifier NCT06859424. Target conditions include AML (Acute Myelogenous Leukemia), Acute Lymphoid Leukemia (ALL), Acute Leukemia (Category).

What happened to similar drugs?

1 of 1 similar drugs in AML (Acute Myelogenous Leukemia) were approved

Approved (1) Terminated (0) Active (0)

Hype Score Breakdown

Clinical
12
Activity
15
Company
12
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT06859424Phase 2Recruiting

Competing Products

6 competing products in AML (Acute Myelogenous Leukemia)

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Gilteritinib + Venetoclax + Azacitidine (AZA) + Local standard of care (SOC)Astellas PharmaPhase 2/3
45
ticagrelor 90 mgAstraZenecaPre-clinical
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Roflumilast + PlaceboAstraZenecaPhase 2
27
milatuzumabGilead SciencesPhase 1
21
Olutasidenib + CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP3A4, and OATP1B1 Probe SubstratesRigel PharmaceuticalsApproved
44
p.DOM-WT1-37 DNA Vaccine and p.DOM-WT1-126 DNA VaccineInovio PharmaceuticalsPhase 2
25