Combindation treatment with Grazoprevir and Elbasvir fixed dose combination tablet, with or without ribavirin

ApprovedWithdrawn

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Interest: 35/100

Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

✓

Phase 2

✓

Phase 3

Approved

Indication / Disease

Cardiac Transplant Disorder

Conditions

Cardiac Transplant Disorder, Hepatitis C

Trial Timeline

Aug 1, 2018 → Jun 30, 2021

NCT ID

NCT03026023

About Combindation treatment with Grazoprevir and Elbasvir fixed dose combination tablet, with or without ribavirin

Combindation treatment with Grazoprevir and Elbasvir fixed dose combination tablet, with or without ribavirin is a approved stage product being developed by Merck for Cardiac Transplant Disorder. The current trial status is withdrawn. This product is registered under clinical trial identifier NCT03026023. Target conditions include Cardiac Transplant Disorder, Hepatitis C.

What happened to similar drugs?

4 of 14 similar drugs in Cardiac Transplant Disorder were approved

Approved (4) Terminated (2) Active (8)

✅Everolimus + Mycophenolic acid (MPA)/azathioprine (AZA) + Calcineurin inhibitors (CNI) + SteroidsNovartisApproved

✅Everolimus + Mycophenolate mofetil + EverolimusNovartisApproved

✅EpinephrinePfizerApproved

✅Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM)Mochida PharmaceuticalApproved

🔄Edoxaban + Standard of Care (SOC)Daiichi SankyoPhase 3

🔄Everolimus (RAD001)NovartisPhase 3

❌Ranolazine + PlaceboGilead SciencesPhase 3

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (1)

NCT ID	Phase	Status	Start	Completion	Indication
NCT03026023	Approved	Withdrawn	Aug 1, 2018	Jun 30, 2021	Cardiac Transplant Disorder

Competing Products

20 competing products in Cardiac Transplant Disorder

See all competitors

Product	Company	Stage	Hype Score
Edoxaban + Standard of Care (SOC)	Daiichi Sankyo	Phase 3	40
regadenoson	Astellas Pharma	Pre-clinical	26
Baricitinib (LY3009104) 4 mg	Eli Lilly	Phase 2	42
Current Domperidone + Current proton pump inhibitor (PPI)	Johnson & Johnson	Pre-clinical	26
Everolimus (RAD001)	Novartis	Phase 3	40
Deferasirox and Deferoxamine	Novartis	Phase 2	35
Everolimus + Mycophenolic acid (MPA)/azathioprine (AZA) + Calcineurin inhibitors (CNI) + Steroids	Novartis	Approved	43
TIN816	Novartis	Phase 2	27
Everolimus + Mycophenolate mofetil + Everolimus	Novartis	Approved	43
Pirfenidone + Placebo	Roche	Phase 2	35
Daclizumab	Roche	Phase 1/2	24
Ranolazine + Placebo	Gilead Sciences	Phase 3	32
Insulin infusion with a goal	Novo Nordisk	Phase 3	40
Epinephrine	Pfizer	Approved	50
sitaxsentan (Thelin) + sitaxsentan (Thelin) + Placebo	Pfizer	Phase 2	35
Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM)	Mochida Pharmaceutical	Approved	43
BMS-986224	Bristol Myers Squibb	Phase 1	29
BMS-986231 + Furosemide + Placebo	Bristol Myers Squibb	Phase 2	35
Balinatunfib + Moxifloxacin + Placebo	Sanofi	Phase 1	36
Sotagliflozin + Placebo	Sanofi	Phase 2	27