BiotechTube

CFT1946 + Trametinib + Cetuximab

Phase 1Completed
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Interest: 19/100
19
Hype Score

Development Stage

✓
Pre-clinical
2
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Solid Tumors

Conditions

Solid Tumors, Melanoma, NSCLC, CRC, ATC

Trial Timeline

Dec 8, 2022 → Nov 5, 2025

NCT ID
NCT05668585

About CFT1946 + Trametinib + Cetuximab

CFT1946 + Trametinib + Cetuximab is a phase 1 stage product being developed by C4 Therapeutics for Solid Tumors. The current trial status is completed. This product is registered under clinical trial identifier NCT05668585. Target conditions include Solid Tumors, Melanoma, NSCLC.

What happened to similar drugs?

5 of 13 similar drugs in Solid Tumors were approved

Approved (5) Terminated (2) Active (8)
✅DurvalumabAstraZenecaApproved
✅ARM A : IV iron + epoietin zeta + ARM B: IV iron + epoietin zeta sequence + ARM C : single epoietin zetaRocheApproved
✅denosumab + pamidronateAmgenApproved
✅Sacituzumab Govitecan-hiyGilead SciencesApproved
✅Binimetinib only treatment + Encorafenib only Treatment + Encorafenib & Binimetinib Treatment + Treatment of Encorafenib & Binimetinib & Ribociclib + Treatment of Encorafenib & Binimetinib & CetuximabPfizerApproved
🔄olanzapine plus fosaprepitant-based triple regimen + placebo plus fosaprepitant-based triple regimenSun PharmaceuticalPhase 3
🔄MEDI4736 (Durvalumab) + MEDI4736 (Durvalumab) + TremelimumabAstraZenecaPhase 3

Hype Score Breakdown

Clinical
6
Activity
8
Company
5
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT05668585Phase 1Completed

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0
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33
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0
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14
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11
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18
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18
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27
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18
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30
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22
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26