Carbidopa/levodopa/entacapone

ApprovedCompleted

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Interest: 43/100

Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

✓

Phase 2

✓

Phase 3

Approved

Indication / Disease

Parkinson's Disease With End of Dose Wearing Off

Conditions

Parkinson's Disease With End of Dose Wearing Off

Trial Timeline

Jan 1, 2005 → Jul 1, 2008

NCT ID

NCT00219284

About Carbidopa/levodopa/entacapone

Carbidopa/levodopa/entacapone is a approved stage product being developed by Novartis for Parkinson's Disease With End of Dose Wearing Off. The current trial status is completed. This product is registered under clinical trial identifier NCT00219284. Target conditions include Parkinson's Disease With End of Dose Wearing Off.

What happened to similar drugs?

20 of 20 similar drugs in Parkinson's Disease With End of Dose Wearing Off were approved

Approved (20) Terminated (4) Active (0)

✅Lemborexant + placeboEisaiApproved

✅Levodopa-carbidopa intestinal gel (LCIG)AbbVieApproved

✅Carbidopa/levodopa/entacapone + Immediate release carbidopa/levodopaNovartisApproved

✅carbidopa/levodopa + Carbidopa/Levodopa/EntacaponeNovartisApproved

✅carbidopa, levodopa, entacaponeNovartisApproved

✅Levodopa/carbidopa/entacapone + Levodopa/carbidopaNovartisApproved

✅Cabergoline + LevodopaPfizerApproved

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (1)

NCT ID	Phase	Status	Start	Completion	Indication
NCT00219284	Approved	Completed	Jan 1, 2005	Jul 1, 2008	Parkinson's Disease With End of Dose Wearing Off

Competing Products

20 competing products in Parkinson's Disease With End of Dose Wearing Off

See all competitors

Product	Company	Stage	Hype Score
UB-312 + Placebo	Vaxxinity	Phase 1	19
NAV5001 + DaTscan	Navidea Biopharmaceuticals	Phase 3	22
piclozotan + 0.9% sodium chloride (normal saline)	Daiichi Sankyo	Phase 2	35
E2007	Eisai	Phase 3	32
ARICEPT	Eisai	Phase 3	40
Perampanel	Eisai	Phase 3	32
GPI 1485	Eisai	Phase 2	35
E2007	Eisai	Phase 3	40
Prior Donepezil 5mg + Prior Donzepezil 10mg + Prior Placebo	Eisai	Phase 3	40
perampanel + placebo	Eisai	Phase 2	27
Lemborexant + placebo	Eisai	Approved	50
Placebo + E2007 + E2007	Eisai	Phase 3	32
E2007 + E2007 + E2007	Eisai	Phase 2	35
E2007	Eisai	Phase 2	35
E2007	Eisai	Phase 2	27
E2007	Eisai	Phase 2	27
2 mg perampanel + 4 mg perampanel + placebo comparator	Eisai	Phase 3	40
Istradefylline (KW-6002)	Kyowa Kirin	Phase 2	35
Istradefylline 20 mg or 40 mg	Kyowa Kirin	Phase 3	40
Istradefylline (KW-6002)	Kyowa Kirin	Phase 3	40