Bupivacaine HCI without epinephrine + HTX-011

Phase 2Completed

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Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Post-Operative Pain

Conditions

Post-Operative Pain, Lumbar Laminectomy

Trial Timeline

Apr 7, 2022 → Aug 26, 2022

NCT ID

NCT04911062

About Bupivacaine HCI without epinephrine + HTX-011

Bupivacaine HCI without epinephrine + HTX-011 is a phase 2 stage product being developed by Heron Therapeutics for Post-Operative Pain. The current trial status is completed. This product is registered under clinical trial identifier NCT04911062. Target conditions include Post-Operative Pain, Lumbar Laminectomy.

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (1)

NCT ID	Phase	Status	Start	Completion	Indication
NCT04911062	Phase 2	Completed	Apr 7, 2022	Aug 26, 2022	Post-Operative Pain

Competing Products

18 competing products in Post-Operative Pain

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Product	Company	Stage	Hype Score
Qutenza	Astellas Pharma	Pre-clinical	23
Test naproxen sodium tablet + Commercial naproxen sodium tablet + Commercial naproxen sodium liquid gels capsule + Placebo tablet	Johnson & Johnson	Phase 3	77
Test acetaminophen + Commercial acetaminophen + Commercial ibuprofen + Placebo	Johnson & Johnson	Phase 3	77
Paracetamol injection + Normal Saline injection + Morhpine PCA	Jiangsu Hengrui Medicine	Phase 2/3	65
AGN-151607 + Placebo	AbbVie	Phase 2	52
Comparator: MK0517 + Comparator: ondansetron	Merck	Phase 3	77
Sugammadex + Neostigmine + Atropine + Rocuronium + Fentanyl + Propofol + Sevoflurane	Merck	Approved	85
Aprepitant + Placebo to Aprepitant + Ondansetron + Placebo to match ondansetron	Merck	Phase 2	52
granisetron + granisetron	Roche	Approved	85
Parecoxib Sodium	Pfizer	Approved	84
lyrica	Pfizer	Phase 3	76
Placebo + Pregabalin + Pregabalin	Pfizer	Phase 1	32
Methylnaltrexone + Placebo	Pfizer	Phase 3	76
HSK16149 capsule + Placebo	Haisco Pharmaceutical Group	Phase 2	49
Ropivacaine	Lundbeck	Approved	82
Sufentanil NanoTab PCA System/15 mcg + morphine IV PCA	Talphera	Phase 3	69
Sufentanil NanoTab PCA System/15 mcg + Placebo Sufentanil NanoTab PCA System	Talphera	Phase 3	69
Sufentanil Tablet 30 mcg + Placebo Tablet	Talphera	Phase 3	69

Other Products from Heron Therapeutics

SUSTOLApproved

HTX-011 + Bupivacaine Hydrochloride + Ibuprofen + AcetaminophenApproved

Bupivacaine HClApproved

HTX-011 + Bupivacaine Hydrochloride + Ibuprofen + AcetaminophenApproved

Bupivacaine liposome injectable suspension + Bupivacaine HCl without epinephrine via continuous infusionApproved