BiotechTube

Benralizumab 30 mg + Matched placebo

Phase 3Terminated
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Interest: 32/100
32
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
✓
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Nasal Polyposis

Conditions

Nasal Polyposis, Eosinophilic Chronic Rhinosinusitis

Trial Timeline

Nov 25, 2019 → Apr 7, 2025

NCT ID
NCT04157335

About Benralizumab 30 mg + Matched placebo

Benralizumab 30 mg + Matched placebo is a phase 3 stage product being developed by AstraZeneca for Nasal Polyposis. The current trial status is terminated. This product is registered under clinical trial identifier NCT04157335. Target conditions include Nasal Polyposis, Eosinophilic Chronic Rhinosinusitis.

What happened to similar drugs?

8 of 20 similar drugs in Nasal Polyposis were approved

Approved (8) Terminated (2) Active (12)
✅Diphenhydramine 50 mg + Diphenhydramine 25 mg + Pseudoephedrine 120 mgJohnson & JohnsonApproved
✅Budesonide NasalJohnson & JohnsonApproved
✅mometasone furoateMerckApproved
✅Dupilumab SAR231893SanofiApproved
✅DupilumabSanofiApproved
✅Dupilumab + Omalizumab + PlaceboSanofiApproved
✅Dupilumab Prefilled SyringeRegeneron PharmaceuticalsApproved

Hype Score Breakdown

Clinical
17
Activity
0
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT04157335Phase 3Terminated

Competing Products

20 competing products in Nasal Polyposis

See all competitors
ProductCompanyStageHype Score
Avastin + Gemcitabine + Oxaliplatin + Pegaspargase + DexamethasoneEli LillyPhase 2
31
Rabeprazole 20 mg twice a day for 90-day period treatmentEisaiPhase 2
35
High dose of methotrexate + Gemcitabine + Pegaspargase + DexamethasoneEli LillyPhase 2
31
LY3650150 + Placebo + Standard therapy for INCSEli LillyPhase 3
47
Diphenhydramine 50 mg + Diphenhydramine 25 mg + Pseudoephedrine 120 mgJohnson & JohnsonApproved
43
xylo+dex nasal spray (0.1 mg+5 mg/dose) + NasicJohnson & JohnsonPhase 3
40
Budesonide NasalJohnson & JohnsonApproved
47
Diphenhydramine hydrochlorideJohnson & JohnsonPhase 1
29
SHR-1210Jiangsu Hengrui MedicinePhase 2
31
Experimental: Tezepelumab + Mometasone furoate or equivalent intranasal corticosteroidAstraZenecaPhase 3
40
Benralizumab 30 mg SC + Mometasone Furoate + Matching placebo SC + Mometasone FuroateAstraZenecaPhase 3
40
Benralizumab + PlaceboAstraZenecaPhase 3
40
Pembrolizumab + Cisplatin + Docetaxel + CarboplatinMerckPhase 2
42
mometasone furoateMerckApproved
35
Fevipiprant 150 mg + Fevipiprant 450 mg + PlaceboNovartisPhase 3
40
Omalizumab + PlaceboNovartisPhase 2
35
Omalizumab + PlaceboRochePhase 3
40
Omalizumab + PlaceboRochePhase 3
40
Omalizumab + PlaceboRochePhase 3
40
carfilzomibAmgenPhase 1
29