Aprepitant + Palonosetron + Dexamethasone

Phase 2UNKNOWN
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Interest: 31/100
31
Hype Score

Development Stage

Pre-clinical
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Chemotherapy-Induced Nausea and Vomiting

Conditions

Chemotherapy-Induced Nausea and Vomiting, Lung Cancer

Trial Timeline

Dec 1, 2015 → May 1, 2016

About Aprepitant + Palonosetron + Dexamethasone

Aprepitant + Palonosetron + Dexamethasone is a phase 2 stage product being developed by Merck for Chemotherapy-Induced Nausea and Vomiting. The current trial status is unknown. This product is registered under clinical trial identifier NCT02445872. Target conditions include Chemotherapy-Induced Nausea and Vomiting, Lung Cancer.

What happened to similar drugs?

3 of 20 similar drugs in Chemotherapy-Induced Nausea and Vomiting were approved

Approved (3) Terminated (4) Active (14)
Pregabalin + PlaceboPfizerApproved
SUSTOLHeron TherapeuticsApproved
🔄GranisetronKyowa KirinPhase 3
🔄Hetrombopag + Hetrombopag plus Placebo + PlaceboJiangsu Hengrui MedicinePhase 3
Hetrombopag + Matching placeboJiangsu Hengrui MedicinePhase 3

Hype Score Breakdown

Clinical
12
Activity
4
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT02445872Phase 2UNKNOWN

Competing Products

20 competing products in Chemotherapy-Induced Nausea and Vomiting

See all competitors
ProductCompanyStageHype Score
SON-080Sonnet BioTherapeuticsPhase 1/2
18
GranisetronKyowa KirinPhase 3
40
ONO-7746Ono PharmaceuticalPhase 1
21
ONO-2910 + PlaceboOno PharmaceuticalPhase 2
35
PROCRIT 40,000 IU QW + PlaceboJohnson & JohnsonPhase 2
27
Hetrombopag Olamine + Hetrombopag Olamine ;Hetrombopag Olamine PlaceboJiangsu Hengrui MedicinePhase 3
47
Hetrombopag OlamineJiangsu Hengrui MedicinePhase 2
42
Hetrombopag + Hetrombopag plus Placebo + PlaceboJiangsu Hengrui MedicinePhase 3
44
Hetrombopag + Matching placeboJiangsu Hengrui MedicinePhase 3
32
Hetrombopag + PlaceboJiangsu Hengrui MedicinePhase 3
40
Fosaprepitant dimeglumine + Fosaprepitant Placebo + Dexamethasone + Ondansetron + Dexamethasone Placebo + Ondansetron Placebo + Rescue TherapyMerckPhase 3
40
FosaprepitantMerckPhase 2
27
Fosaprepitant + Placebo for fosaprepitant + Ondansetron + Dexamethasone + 5-HT3 antagonistMerckPhase 3
32
Fosaprepitant + Dexamethasone + 5HT3MerckPhase 2
35
aprepitant + Comparator: Placebo to aprepitant + dexamethasone + granisetron + dexamethasoneMerckPhase 3
40
aprepitant + Comparator: ondansetron + Comparator: dexamethasone + Comparator: fosaprepitant dimeglumine + Comparator; Placebo (unspecified) + Comparator; Placebo (unspecified)MerckPhase 3
40
EMENDMerckPre-clinical
26
Fosaprepitant Dimeglumine + 5-HT3 antagonist + DexamethasoneMerckApproved
43
ondansetron clinical trial formulation + ondansetron marketed formulationMerckPhase 1
29
Fosaprepitant 150 mg + Aprepitant 165 mg + Aprepitant 250 mg + Dexamethasone (12-8-16-16 mg) + Dexamethasone (12-8-8-16 mg) + Ondansetron + MK0999MerckPhase 1
29