APR-246 + azacitidine + Azacitidine
Phase 3Completed 0 watching 0 views this week📈 Rising
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Development Stage
✓
Pre-clinical✓
Phase 1✓
Phase 24
Phase 35
ApprovedAbout APR-246 + azacitidine + Azacitidine
APR-246 + azacitidine + Azacitidine is a phase 3 stage product being developed by Aprea Therapeutics for MDS. The current trial status is completed. This product is registered under clinical trial identifier NCT03745716. Target conditions include MDS.
Hype Score Breakdown
Clinical
27
Activity
18
Company
2
Novelty
9
Community
10
Clinical Trials (1)
| NCT ID | Phase | Status |
|---|---|---|
| NCT03745716 | Phase 3 | Completed |
Competing Products
20 competing products in MDS
| Product | Company | Stage | Hype Score |
|---|---|---|---|
| NEX-18a injection + Azacitidine Injection | Nanexa AB | Phase 1 | 28 |
| Humanized anti-CD117 Monoclonal Antibody (JSP191) | Jasper Therapeutics | Phase 1 | 25 |
| Roxadustat + Placebo | Astellas Pharma | Phase 3 | 77 |
| KRN321 | Kyowa Kirin | Phase 2 | 52 |
| Azacitidine + Venetoclax | AbbVie | Phase 1 | 33 |
| venetoclax + azacitidine | AbbVie | Phase 1 | 33 |
| Venetoclax + Azacitidine + Placebo | AbbVie | Phase 3 | 77 |
| venetoclax + azacitidine +/- donor lymphocyte infusion | AbbVie | Phase 1/2 | 41 |
| Birabresib Dose 20 mg | Merck | Phase 1 | 33 |
| Azacitidine and LDE255 | Novartis | Phase 1 | 33 |
| MBG453 + Azacitidine + Decitabine + INQOVI (oral decitabine) | Novartis | Phase 2 | 52 |
| Panobinostat | Novartis | Phase 2 | 52 |
| Azacitidine + Azacitidine plus Deferasirox | Novartis | Phase 2 | 52 |
| Deferasirox, Vitamin D and Azacitidine | Novartis | Phase 1/2 | 41 |
| LGH447 + LGH447 + midostaurin | Novartis | Phase 1 | 33 |
| Panobinostat | Novartis | Phase 1 | 33 |
| sabatolimab + azacitidine + venetoclax | Novartis | Phase 2 | 52 |
| LBH589 + Epoetin Alfa | Novartis | Phase 2 | 52 |
| Placebo + Romiplostim | Amgen | Phase 2 | 51 |
| Darbepoetin alfa + Placebo | Amgen | Phase 3 | 76 |
Other Products from Aprea Therapeutics
APR-246Phase 2
44
APR-246 + Pegylated Liposomal Doxorubicin Hydrochloride (PLD)Phase 2
44
APR-246 + Carboplatin and Pegylated Liposomal Doxorubicin Hydrochloride (PLD)Phase 1/2
33
APR-246 (eprenetapopt) + Acalabrutinib in CLL + APR-246 (eprenetapopt) 4.5 g/d + Venetoclax + Rituximab in CLL + APR-246 (eprenetapopt) 4.5 g/d + (Acalabrutinib, OR, (Venetoclax +Rituximab)), in CLL and/or MCL and/or RT + APR-246 (eprenetapopt) 4.5 g/d + Venetoclax + Rituximab in RTPhase 1/2
33
APR-246 + AzacitidinePhase 1/2
33