APL-2, Pegcetacoplan

Phase 3Completed
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Interest: 34/100
34
Hype Score

Development Stage

Pre-clinical
Phase 1
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Geographic Atrophy Secondary to Age-related Macular Degeneration

Conditions

Geographic Atrophy Secondary to Age-related Macular Degeneration

Trial Timeline

Oct 24, 2025 → Dec 12, 2025

About APL-2, Pegcetacoplan

APL-2, Pegcetacoplan is a phase 3 stage product being developed by Apellis Pharmaceuticals for Geographic Atrophy Secondary to Age-related Macular Degeneration. The current trial status is completed. This product is registered under clinical trial identifier NCT07214740. Target conditions include Geographic Atrophy Secondary to Age-related Macular Degeneration.

What happened to similar drugs?

1 of 11 similar drugs in Geographic Atrophy Secondary to Age-related Macular Degeneration were approved

Approved (1) Terminated (3) Active (7)
avacincaptad pegolAstellas PharmaApproved
🔄avacincaptad pegolAstellas PharmaPhase 3
🔄Avacincaptad Pegol + ShamAstellas PharmaPhase 3
LampalizumabRochePhase 3
LampalizumabRochePhase 3
LampalizumabRochePhase 3
🔄Tinlarebant + PlaceboBelite BioPhase 3

Hype Score Breakdown

Clinical
17
Activity
8
Company
9
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT07214740Phase 3Completed

Competing Products

20 competing products in Geographic Atrophy Secondary to Age-related Macular Degeneration

See all competitors
ProductCompanyStageHype Score
avacincaptad pegolAstellas PharmaPhase 3
40
Avacincaptad PegolAstellas PharmaPhase 2/3
38
avacincaptad pegolAstellas PharmaApproved
50
Avacincaptad pegol (ACP)Astellas PharmaPre-clinical
33
Avacincaptad Pegol + ShamAstellas PharmaPhase 3
40
ABBV-6628 + SYFOVREAbbViePhase 1/2
39
FWY003 + PlaceboNovartisPhase 2
42
CLG561 + LFG316 + Sham injectionNovartisPhase 2
35
LFG316 + Sham + LFG316 Lower doseNovartisPhase 2
35
LampalizumabRochePhase 3
32
LampalizumabRochePhase 3
32
LampalizumabRochePhase 3
32
RO7669330 + Syfovre™ + Izervay™RochePhase 1
36
RO7303359RochePhase 1
29
SAR446597 + Sham ComparatorSanofiPhase 1/2
39
PozelimabRegeneron PharmaceuticalsPhase 1
36
IONIS-FB-Lrx + Placebo (sterline saline 0.9%)Ionis PharmaceuticalsPhase 2
24
Tinlarebant + PlaceboBelite BioPhase 3
41
PegcetacoplanApellis PharmaceuticalsPre-clinical
24
APL-2 + APL-2Apellis PharmaceuticalsPhase 3
34