BiotechTube

Abemaciclib + Irinotecan + Temozolomide

Phase 2Active
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Interest: 39/100
39
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Sarcoma, Ewing

Conditions

Sarcoma, Ewing, Neoplasm Metastasis

Trial Timeline

Sep 20, 2022 → Sep 1, 2028

NCT ID
NCT05440786

About Abemaciclib + Irinotecan + Temozolomide

Abemaciclib + Irinotecan + Temozolomide is a phase 2 stage product being developed by Eli Lilly for Sarcoma, Ewing. The current trial status is active. This product is registered under clinical trial identifier NCT05440786. Target conditions include Sarcoma, Ewing, Neoplasm Metastasis.

What happened to similar drugs?

1 of 15 similar drugs in Sarcoma, Ewing were approved

Approved (1) Terminated (1) Active (13)
🔄Abemaciclib + PlaceboEli LillyPhase 3
🔄cisplatin + doxorubicin hydrochloride + etoposide + ifosfamide + methotrexate + zoledronic acidChugai PharmaceuticalPhase 3
🔄Eribulin mesylate 1.4 mg/m^2 intravenous + Dacarbazine of 850 mg/m^2, or 1,000 mg/m^2, or 1,200 mg/m^2 IVEisaiPhase 3
🔄Olaratumab + Doxorubicin + PlaceboEli LillyPhase 3
🔄Trabectedin + Doxorubicin + IfosfamideJohnson & JohnsonPhase 3
❌LV305 + G305MerckPhase 3
✅Lopinavir/ritonavir plus Emtricitabine/Tenofovir versus Efavirenz plus Emtricitabine/TenofovirMerckApproved

Hype Score Breakdown

Clinical
12
Activity
12
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT05440786Phase 2Active

Competing Products

20 competing products in Sarcoma, Ewing

See all competitors
ProductCompanyStageHype Score
Tc99m-tilmanoceptNavidea BiopharmaceuticalsPhase 1
19
Azenosertib + GemcitabineZentalis PharmaceuticalsPhase 1/2
22
Olaratumab + Doxorubicin + Ifosfamide + MesnaEli LillyPhase 1
29
CAB-AXL-ADC + PD-1 inhibitorBioAtlaPhase 1/2
22
AbemaciclibEli LillyPhase 2
39
Abemaciclib + PlaceboEli LillyPhase 3
44
cisplatin + doxorubicin hydrochloride + etoposide + ifosfamide + methotrexate + zoledronic acidChugai PharmaceuticalPhase 3
44
PLX3397 + sirolimusDaiichi SankyoPhase 1/2
24
exatecan mesylateDaiichi SankyoPhase 2
35
efatutazoneDaiichi SankyoPhase 2
35
soblidotinDaiichi SankyoPhase 2
35
exatecan mesylateDaiichi SankyoPhase 2
35
LinsitinibAstellas PharmaPhase 2
35
Fluzoparib+ DalpiciclibSun PharmaceuticalPhase 2
31
Anlotinib HydrochlorideSun PharmaceuticalPhase 2
31
Doxorubicin Hydrochloride Liposome+Irinotecan + Temozolomide+Irinotecan+VincristineSun PharmaceuticalPhase 2
42
irinotecan liposome (II) + temozolomide + fluzoparibSun PharmaceuticalPhase 2
42
Eribulin mesylate 1.4 mg/m^2 intravenous + Dacarbazine of 850 mg/m^2, or 1,000 mg/m^2, or 1,200 mg/m^2 IVEisaiPhase 3
40
EribulinEisaiPhase 2
39
Lenvatinib + Ifosfamide + Etoposide + LenvatinibEisaiPhase 2
35