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Zerlasiran (SLN360)

Elevated Lipoprotein(a) for Cardiovascular Risk Reduction

Phase 2Active

Key Facts

Indication
Elevated Lipoprotein(a) for Cardiovascular Risk Reduction
Phase
Phase 2
Status
Active
Company

About Silence Therapeutics

Silence Therapeutics is a UK-based pioneer in RNA interference (RNAi) therapeutics, utilizing its proprietary mRNAi GOLD™ platform to design targeted siRNA medicines. The company has validated its technology through significant partnerships with AstraZeneca and Hansoh Pharma, while advancing its internal lead asset, zerlasiran (SLN360), for cardiovascular disease. Its strategy balances internal pipeline development in cardiometabolic and hematologic diseases with platform licensing, aiming to create a sustainable biotech with multiple value inflection points.

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Olpasiran (AMG 890)AmgenPhase 3