Home/Pipeline/Zabalafin Hydrogel (AB-101a)

Zabalafin Hydrogel (AB-101a)

Atopic Dermatitis

Phase 2bActive

Key Facts

Indication
Atopic Dermatitis
Phase
Phase 2b
Status
Active
Company

About Alphyn Biologics

Alphyn Biologics is a private, clinical-stage biotech focused on transformative dermatology treatments. The company leverages its proprietary Zabalafin Platform to develop Multi-Target Therapeutics (MTT) that simultaneously address inflammation, infection, and itch in skin diseases. Its lead program, zabalafin hydrogel, has shown positive Phase 2a results in atopic dermatitis and is now in a global Phase 2b trial, with a second program for molluscum contagiosum also in Phase 2. Founded in 2016 and headquartered in Boston, Alphyn aims to become a leader in dermatology by addressing unmet needs for safe, long-term therapies.

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About Alphyn Biologics

Alphyn Biologics is a private, clinical-stage biotech focused on transformative dermatology treatments. The company leverages its proprietary Zabalafin Platform to develop Multi-Target Therapeutics (MTT) that simultaneously address inflammation, infection, and itch in skin diseases. Its lead program, zabalafin hydrogel, has shown positive Phase 2a results in atopic dermatitis and is now in a global Phase 2b trial, with a second program for molluscum contagiosum also in Phase 2. Founded in 2016 and headquartered in Boston, Alphyn aims to become a leader in dermatology by addressing unmet needs for safe, long-term therapies.

View full company profile

Therapeutic Areas

Other Atopic Dermatitis Drugs

DrugCompanyPhase
PEP Biologic™Intent BiologicsUnknown
HBM7575 (SKB575)Harbour BioMedIND Filed
ITK inhibitorAcelleraPre-clinical
Encube-003Encube EthicalsPreclinical
ENS-002 (Fermata Derm)Concerto BiosciencesPre-clinical
Lead ProgramMatriSys BiosciencePhase 1
Atopic Dermatitis TrialWell Pharma Medical ResearchNot Specified
MEndoBMicreosPre-clinical
Atopic Dermatitis ProgramLxbio PharmaceuticalsPre-clinical
B244AOBiomePhase 3
CTO1681CytoAgentsPre-clinical
DS107DS BiopharmaPhase 2