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VTX-PID

Depletion of Neutralizing Antibodies against AAV

Phase 1/2Active

Key Facts

Indication
Depletion of Neutralizing Antibodies against AAV
Phase
Phase 1/2
Status
Active
Company

About Vivet Therapeutics

Vivet Therapeutics is a private, clinical-stage gene therapy company based in Paris, developing a pipeline of liver-directed AAV-based treatments for rare metabolic diseases such as Wilson's Disease, Cerebrotendinous Xanthomatosis (CTX), and Progressive Familial Intrahepatic Cholestasis (PFIC). A key differentiator is its VTX-PID platform, an imlifidase-based technology designed to deplete neutralizing antibodies against AAV, potentially enabling treatment for a broader patient population and allowing for re-dosing. The company has advanced its lead program, VTX-801 for Wilson's Disease, into clinical trials and has secured Orphan Drug designations from major regulatory agencies, supported by a seasoned leadership team and committed international investors.

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