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Visugromab (CTL-002)

Metastatic Non-squamous Non-Small Cell Lung Cancer (2nd line)

Phase 2bActive - First patient dosed Dec 2025

Key Facts

Indication
Metastatic Non-squamous Non-Small Cell Lung Cancer (2nd line)
Phase
Phase 2b
Status
Active - First patient dosed Dec 2025
Company

About CatalYm

CatalYm is a clinical-stage biotech focused on overcoming cancer therapy resistance by neutralizing GDF-15 (Growth Differentiation Factor-15), a key immunosuppressant hijacked by tumors. The company's lead asset, visugromab, has demonstrated durable objective responses in Phase 1/2a trials in checkpoint inhibitor-refractory metastatic solid tumors. With an experienced leadership team, CatalYm is now expanding its clinical program into Phase 2b studies in non-small cell lung cancer (NSCLC) and other indications, positioning visugromab as a potential backbone combination therapy in immuno-oncology.

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About CatalYm

CatalYm is a clinical-stage biotech focused on overcoming cancer therapy resistance by neutralizing GDF-15 (Growth Differentiation Factor-15), a key immunosuppressant hijacked by tumors. The company's lead asset, visugromab, has demonstrated durable objective responses in Phase 1/2a trials in checkpoint inhibitor-refractory metastatic solid tumors. With an experienced leadership team, CatalYm is now expanding its clinical program into Phase 2b studies in non-small cell lung cancer (NSCLC) and other indications, positioning visugromab as a potential backbone combination therapy in immuno-oncology.

View full company profile

About CatalYm

CatalYm is a clinical-stage biotech focused on overcoming cancer therapy resistance by neutralizing GDF-15 (Growth Differentiation Factor-15), a key immunosuppressant hijacked by tumors. The company's lead asset, visugromab, has demonstrated durable objective responses in Phase 1/2a trials in checkpoint inhibitor-refractory metastatic solid tumors. With an experienced leadership team, CatalYm is now expanding its clinical program into Phase 2b studies in non-small cell lung cancer (NSCLC) and other indications, positioning visugromab as a potential backbone combination therapy in immuno-oncology.

View full company profile

Therapeutic Areas