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VCN-01

Head and Neck Squamous Cell Carcinoma (HNSCC)

Phase 2Active (Investigator-Sponsored Study)N/A (Investigator-Sponsored)

Key Facts

Indication
Head and Neck Squamous Cell Carcinoma (HNSCC)
Phase
Phase 2
Status
Active (Investigator-Sponsored Study)
Company

About Theriva Biologics

Theriva Biologics is advancing a differentiated oncolytic virus platform engineered for systemic intravenous delivery, a key limitation of earlier therapies. Its lead candidate, VCN-01, has demonstrated promising clinical activity in metastatic pancreatic ductal adenocarcinoma (PDAC) and is positioned for a pivotal Phase 3 trial following a positive End-of-Phase 2 FDA meeting. The company's strategy focuses on leveraging its stroma-degrading and Albumin Shield™ technologies to treat difficult-to-treat solid tumors, both as monotherapy and in combination with chemotherapy and immunotherapy.

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About Theriva Biologics

Theriva Biologics is advancing a differentiated oncolytic virus platform engineered for systemic intravenous delivery, a key limitation of earlier therapies. Its lead candidate, VCN-01, has demonstrated promising clinical activity in metastatic pancreatic ductal adenocarcinoma (PDAC) and is positioned for a pivotal Phase 3 trial following a positive End-of-Phase 2 FDA meeting. The company's strategy focuses on leveraging its stroma-degrading and Albumin Shield™ technologies to treat difficult-to-treat solid tumors, both as monotherapy and in combination with chemotherapy and immunotherapy.

View full company profile

Therapeutic Areas

Other Head and Neck Squamous Cell Carcinoma (HNSCC) Drugs

DrugCompanyPhase
Membrex™Metaclipse TherapeuticsPhase 1
CXR101CorriXR TherapeuticsPre-clinical