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Varegacestat (AL102)

Progressing Desmoid Tumors

Phase 3Late-clinical stage; Top-line Phase 3 (RINGSIDE) results announced

Key Facts

Indication
Progressing Desmoid Tumors
Phase
Phase 3
Status
Late-clinical stage; Top-line Phase 3 (RINGSIDE) results announced
Company

About Immunome

Immunome is a clinical-stage biotech dedicated to improving outcomes for cancer patients through a portfolio of targeted therapies, primarily centered on antibody-drug conjugates (ADCs). The company's most advanced asset is varegacestat, a gamma secretase inhibitor in Phase 3 for desmoid tumors, complemented by earlier-stage ADC and radioligand programs. Under the leadership of CEO Clay Siegall, co-founder of Seagen, Immunome leverages significant ADC expertise to pursue differentiated targets and optimize therapeutic candidates for efficacy and tolerability.

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Therapeutic Areas