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Undisclosed PTEC Program(s)

Metabolic disorders (e.g., hyperphosphatemia, hyperuricemia), ADPKD, Ischemia-Reperfusion Injury, Inflammation/Fibrosis

Pre-clinicalActive

Key Facts

Indication
Metabolic disorders (e.g., hyperphosphatemia, hyperuricemia), ADPKD, Ischemia-Reperfusion Injury, Inflammation/Fibrosis
Phase
Pre-clinical
Status
Active
Company

About Hybridize Therapeutics

Hybridize Therapeutics is a private, clinical-stage biotech developing kidney-targeted RNA therapeutics to address a major unmet need in nephrology. Its platform enables the design of chemically modified oligonucleotides with extended half-lives and cell-specific delivery, primarily targeting the proximal tubule epithelial cell (PTEC). The company's lead program, HYB_BKV, is a direct-acting antiviral for BK virus in transplant patients and has been partnered with AiCuris in a deal worth up to €100M, with the program now in Phase 1/2 clinical trials.

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