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Undisclosed CNS Program(s)

Genetic Neurological Disease(s)

Pre-clinicalActive

Key Facts

Indication
Genetic Neurological Disease(s)
Phase
Pre-clinical
Status
Active
Companies

About Editpep

Editpep is a private, pre-clinical stage biotech developing a novel non-viral delivery platform, PERC™, for CRISPR gene editing in vivo. The platform, exclusively licensed from UC Berkeley, is engineered for high-efficiency editing in hard-to-treat tissues like the brain, with advantages in safety, scalability, and cargo flexibility. The company is leveraging its technology to build a pipeline of CNS-targeted therapies and is actively seeking partnerships to expand its reach into other therapeutic areas.

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About NW PharmaTech

NW PharmaTech is a private, clinical-stage biotech founded in 2015, developing improved therapeutics for mental health conditions using its proprietary micelle-based drug delivery technology. The company is advancing a pipeline within the CNS space, with programs targeting conditions like anxiety and psychosis, and is preparing for Phase IIB trials. It operates with a pre-revenue business model, leveraging academic partnerships and a specialized team to bring enhanced, cost-effective treatments to a large and underserved market.

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About Biomia

Biomia is a preclinical-stage biotech leveraging a rational engineering approach to develop nature-inspired small molecules for CNS disorders. Based in Copenhagen and founded in 2017, the company operates as a private, pre-revenue entity building a therapeutic pipeline from its proprietary discovery platform. Its strategy involves translating complex natural product pharmacophores into druggable candidates with improved properties for challenging neurological targets.

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About Kesmalea Therapeutics

Kesmalea Therapeutics is a private, preclinical-stage biotech leveraging its innovative SELFTAC® platform to create a new class of oral, CNS-penetrant protein degraders. The company aims to solve the 'size problem' associated with traditional bifunctional degraders by designing small molecules that self-assemble into active degraders in situ. Backed by a £25 million Series A round co-led by Syncona and Oxford Science Enterprise, Kesmalea is building a pipeline in oncology and CNS with a seasoned leadership team. The company's approach could significantly expand the clinical applicability of targeted protein degradation.

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