Tumor Marking/Immune Activation
Cancer
Pre-clinicalActive
Key Facts
About pHLIP
pHLIP, Inc. is a private, clinical-stage biotech leveraging its unique pH-sensitive peptide platform to enable precise targeting of acidic microenvironments found in solid tumors, inflamed, and fibrotic tissues. Its core technology allows for the selective delivery of payloads—ranging from small molecules and proteins to nanoparticles—either to the cell surface or directly into the cytoplasm, aiming to enhance efficacy and reduce systemic side effects. The company has demonstrated proof-of-concept for tumor targeting in humans and is advancing a pipeline focused on oncology and inflammatory diseases. With its platform-agnostic approach, pHLIP seeks to create novel targeted therapies and improve existing treatment modalities.
View full company profileTherapeutic Areas
Other Cancer Drugs
| Drug | Company | Phase |
|---|---|---|
| Not Specified (Oncology Focus) | Narwhal Bio | Pre-clinical |
| EDM Platform for Genetic Medicine | Coastar Therapeutics | Pre-clinical |
| CO-1 | Caedo Oncology | Pre-clinical |
| Anti-CD99 monoclonal antibody | Caedo Oncology | Discovery/Pre-clinical |
| Anti-HLA class I monoclonal antibody | Caedo Oncology | Discovery/Pre-clinical |
| Triapine® | Nanopharmaceutics | Clinical |
| Ammonium Tetrathiomolybdate | Nanopharmaceutics | Clinical |
| Aza-TdC | Nanopharmaceutics | Clinical |
| Undisclosed Oncology Program(s) | Cell BioEngines | Phase 1 |
| No-alpha IL-2 Mutein | SarcoMed USA | Pre-clinical |
| PMIS Therapeutic | NaturemiRI | Preclinical/Clinical (unspecified) |
| AUM302 (formerly IBL-302) | Inflection Biosciences | Pre-clinical (partnered) |