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Temferon

Newly Diagnosed Unmethylated Glioblastoma Multiforme (GBM)

Phase 1/2Active, RecruitingNCT03866109

Key Facts

Indication
Newly Diagnosed Unmethylated Glioblastoma Multiforme (GBM)
Phase
Phase 1/2
Status
Active, Recruiting
Company

About Genenta Science

Genenta Science is developing a disruptive immuno-gene therapy platform that engineers a patient's own hematopoietic stem cells to produce therapeutic proteins, like interferon-alpha, directly within the tumor microenvironment. This approach aims to overcome the limitations of systemic drug delivery by creating a sustained, localized anti-tumor effect with potentially reduced toxicity. The company's lead program, Temferon, is in Phase 1/2 clinical trials for glioblastoma multiforme, a highly aggressive brain cancer with limited treatment options. Genenta's strategy focuses on validating its platform in high-unmet-need oncology indications, with the potential to expand into other solid tumors and therapeutic areas.

View full company profile

About Genenta Science

Genenta Science is developing a disruptive immuno-gene therapy platform that engineers a patient's own hematopoietic stem cells to produce therapeutic proteins, like interferon-alpha, directly within the tumor microenvironment. This approach aims to overcome the limitations of systemic drug delivery by creating a sustained, localized anti-tumor effect with potentially reduced toxicity. The company's lead program, Temferon, is in Phase 1/2 clinical trials for glioblastoma multiforme, a highly aggressive brain cancer with limited treatment options. Genenta's strategy focuses on validating its platform in high-unmet-need oncology indications, with the potential to expand into other solid tumors and therapeutic areas.

View full company profile