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Rondecabtagene autoleucel (ronde-cel, LYL314)

Aggressive Large B-Cell Lymphoma (Third-line or Later)

PivotalRecruitingNCT05826535

Key Facts

Indication
Aggressive Large B-Cell Lymphoma (Third-line or Later)
Phase
Pivotal
Status
Recruiting
Company

About Lyell Immunopharma

Lyell Immunopharma is a clinical-stage biotechnology company focused on developing next-generation CAR T-cell therapies with the goal of delivering lasting remissions or cures for patients with cancer. The company's approach combines novel CAR constructs, proprietary manufacturing protocols, and T-cell biology insights to generate more potent and persistent T cells. Its lead candidate, ronde-cel, is in pivotal trials for large B-cell lymphoma, while LYL273 is in Phase 1 for metastatic colorectal cancer, representing a significant push into solid tumors. Lyell is a fully integrated company with in-house research, development, and manufacturing capabilities.

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About Lyell Immunopharma

Lyell Immunopharma is a clinical-stage biotechnology company focused on developing next-generation CAR T-cell therapies with the goal of delivering lasting remissions or cures for patients with cancer. The company's approach combines novel CAR constructs, proprietary manufacturing protocols, and T-cell biology insights to generate more potent and persistent T cells. Its lead candidate, ronde-cel, is in pivotal trials for large B-cell lymphoma, while LYL273 is in Phase 1 for metastatic colorectal cancer, representing a significant push into solid tumors. Lyell is a fully integrated company with in-house research, development, and manufacturing capabilities.

View full company profile