Pixel-seq

About TopoGene

TopoGene is a long-standing but niche player in the genomics tools space, having pivoted to focus on a proprietary platform for ultra-high-resolution spatial biology. The company's core innovation is Polony gel stamping, a technology that creates master arrays of DNA features at submicron density, which can be inexpensively replicated over a thousand times. This enables their Pixel-seq application, which aims to capture RNA from the single layer of cells contacting the array, offering potential advantages in resolution for spatial transcriptomics. The company appears to be a small, private entity focused on platform development and research applications.