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PIKFYVE Program

ALS / FTD

Pre-clinicalActive

Key Facts

Indication
ALS / FTD
Phase
Pre-clinical
Status
Active
Company

About AcuraStem

AcuraStem, founded in 2016 and based in Pasadena, CA, is a private, pre-clinical biotech developing disease-modifying therapies for neurodegenerative diseases like ALS and FTD. Its core innovation is the iNeuroRx® platform, which utilizes patient-derived cellular models to identify and validate novel therapeutic targets, aiming to overcome the high failure rates of traditional animal models. The company has built a pipeline targeting mechanisms like PIKFYVE and SYF2 and is led by a team with expertise in neuroscience, stem cell biology, and drug development. AcuraStem is currently pre-revenue and funded by grants and venture capital.

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Other ALS / FTD Drugs

DrugCompanyPhase
AS-241 (UNC13A ASO)AcuraStemPre-clinical