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Pidnarulex (CX-5461)

Solid Tumors with HRD

Phase IActiveNCT04890613

Key Facts

Indication
Solid Tumors with HRD
Phase
Phase I
Status
Active
Company

About Senhwa Biosciences

Senhwa Biosciences is a clinical-stage oncology company developing innovative small molecule inhibitors of the DNA Damage Response (DDR), with its lead asset, silmitasertib (CX-4945), targeting Casein Kinase 2 (CK2). The company has advanced multiple programs into mid-stage clinical trials, exploring both monotherapy and combination strategies in cholangiocarcinoma, medulloblastoma, and COVID-19. Its strategy is to exploit tumor-specific genetic vulnerabilities to achieve synthetic lethality and enhance the efficacy of existing cancer therapies, positioning itself in the high-growth targeted oncology and DDR inhibitor space.

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Therapeutic Areas