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PDE4 Allosteric Modulator Program

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Pre-clinicalActive

Key Facts

Indication
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Phase
Pre-clinical
Status
Active
Company

About Mironid

Mironid is a private, preclinical-stage biotech developing first-in-class small molecules for ADPKD and other rare diseases with high unmet need. Its core technology involves the allosteric modulation of long-form PDE4 enzymes, a novel mechanism intended to be disease-modifying. Led by an experienced team with backgrounds at Merck, GSK, and other biopharma firms, the company is building a pipeline and positioning itself as a future leader in PDE therapeutics. Mironid is currently pre-revenue and focused on advancing its research programs to key value inflection points.

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Therapeutic Areas

Other Autosomal Dominant Polycystic Kidney Disease (ADPKD) Drugs

DrugCompanyPhase
Oxypurinol (XRX-OXY)XORTX TherapeuticsPhase 3
TAK-186 (Goreisan)TakedaPhase 2
UndisclosedGondolaBioIND Enabling
Undisclosed ProgramCalicoPhase 2
Small Molecule Corrector ProgramRenasant BioPre-clinical
Small Molecule Potentiator ProgramRenasant BioPre-clinical
AL1311AceLink TherapeuticsPreclinical
TamibaroteneRege NephroPreclinical
TolvaptanOtsuka HoldingsApproved
PXL-770ScynexisPhase 2-ready