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Parkinson's Program

Parkinson's Disease

Pre-clinicalActive

Key Facts

Indication
Parkinson's Disease
Phase
Pre-clinical
Status
Active
Companies

About Araclon Biotech

Araclon Biotech, founded in 2004 and based in Zaragoza, Spain, is a Grifols subsidiary dedicated to tackling Alzheimer's Disease through early diagnostics and active immunotherapy. Its core technology platform centers on measuring amyloid-beta peptides (Aβ40 and Aβ42) in blood plasma, providing a less invasive alternative to cerebrospinal fluid or PET imaging for early detection. The company's lead therapeutic candidate, ABvac40, is an active vaccine targeting the Aβ40 peptide, and it has begun preclinical research into Parkinson's disease through a collaboration with the Spanish National Research Council (CSIC). As a fully integrated R&D unit within Grifols, Araclon leverages its parent company's resources while pursuing a high-risk, high-reward strategy in the neurodegenerative disease space.

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About ProMIS Neurosciences

ProMIS Neurosciences is a clinical-stage biotech leveraging its proprietary EpiSelect™ computational platform to design selective antibodies against toxic misfolded proteins in neurodegenerative diseases. Its lead program, PMN310 for Alzheimer's disease, is in a Phase 1b trial and has received FDA Fast Track designation, with a strategic goal of advancing directly to a registrational study. The company, headquartered in Toronto and Cambridge, is publicly traded on Nasdaq (PMN) and secured a significant financing package in early 2026, extending its cash runway through 2027.

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Other Parkinson's Disease Drugs

DrugCompanyPhase
NPT200-11Neuropore TherapiesPhase 1
VXX-301VaxxinityPreclinical
BAN2802BioArcticPhase 1
CNM-Au8ClenePhase 2
hpSC-Derived Neural/Dopaminergic CellsInternational Stem CellPreclinical/Early Clinical
SLS-004Seelos TherapeuticsPreclinical
SLS-007Seelos TherapeuticsPreclinical
Parkinson's Disease ResearchProgenaBiomeResearch
A9 Dopaminergic Neuron TherapyTrailhead BiosystemsPre-clinical
golexanoloneUmecrine CognitionPreclinical
Bezisterim (NE3107)BioViePhase 2
Cannabinoid-based TherapyGb SciencesPreclinical