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ONO-4685

T-Cell Lymphoma, R/R

Phase 1Active

Key Facts

Indication
T-Cell Lymphoma, R/R
Phase
Phase 1
Status
Active
Companies

About Deciphera Pharmaceuticals

Deciphera Pharmaceuticals is a commercial-stage oncology company with a core focus on developing novel kinase inhibitors using its proprietary switch-control platform. Its achievements include the 2020 FDA approval of QINLOCK for advanced GIST and the 2025 approval of ROMVIMZA for TGCT, solidifying its transition to a commercial entity. Following its 2024 acquisition by Japan's ONO Pharmaceutical, Deciphera now operates as a key U.S./European subsidiary, leveraging enhanced resources to advance a robust, diversified pipeline. The company's strategy centers on overcoming drug resistance in cancer and expanding into new therapeutic areas through internal R&D and strategic collaboration.

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About Ono Pharmaceutical

Ono Pharmaceutical's mission is to address unmet medical needs through the discovery and development of first-in-class and best-in-class therapeutic agents. The company has achieved global recognition primarily through its strategic alliance with Bristol Myers Squibb on the blockbuster PD-1 inhibitor Opdivo (nivolumab), which established its strong foothold in immuno-oncology. Its strategy centers on sustained internal R&D investment, complemented by strategic partnerships and in-licensing to expand its pipeline and global commercial reach. Ono is now executing a multi-faceted growth plan to diversify its portfolio beyond Opdivo and solidify its position as a global specialty pharma leader.

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