NV103/NV105
Glioblastoma, Ovarian Cancer, Pancreatic Cancer, Ewing Sarcoma (CD99-expressing)
Pre-clinicalActive
Key Facts
Indication
Glioblastoma, Ovarian Cancer, Pancreatic Cancer, Ewing Sarcoma (CD99-expressing)
Phase
Pre-clinical
Status
Active
Company
About Nanovalent Pharmaceuticals
Nanovalent Pharmaceuticals is a preclinical-stage biotech leveraging its unique Hybrid Polymerized Liposomal Nanoparticle (HPLN) platform to create next-generation targeted nanotherapeutics, termed nADC/TNS. The company's lead candidate, NV103/NV105, is approaching IND status and targets CD99-expressing tumors such as glioblastoma, Ewing sarcoma, pancreatic, and ovarian cancers. Its platform aims to overcome limitations of traditional ADCs by enabling higher drug payloads, enhanced tumor targeting, and reduced systemic toxicity, with potential applications beyond oncology in neurological diseases due to blood-brain barrier penetration.
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