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NN-843

Alzheimer's Disease

PreclinicalActive

Key Facts

Indication
Alzheimer's Disease
Phase
Preclinical
Status
Active
Company

About NanoNewron

NanoNewron is a private, preclinical-stage biotech based in San Diego, spun out from Rutgers University, with a mission to treat neurodegenerative diseases by enabling biologic delivery across the Blood-Brain Barrier. The company's patented NewroBus™ platform utilizes humanized camelid nanobodies that exploit Transferrin Receptor 1 (TfR1)-mediated transcytosis to shuttle therapeutic payloads into the brain. Its lead program, NN-843, targets Tumor Necrosis Factor-alpha (TNF-α) for Alzheimer's Disease, a pathway with strong scientific rationale but previously inaccessible to approved biologics. The company is led by an experienced team, including CEO Marco Taglietti, who has a track record of bringing drugs to market, and founder/CSO Dr. Luciano D'Adamio, a distinguished neuroscientist.

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