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Naltrexone-Acetaminophen Combination

Acute Migraine

Phase 2Active

Key Facts

Indication
Acute Migraine
Phase
Phase 2
Status
Active
Company

About Allodynic Therapeutics

Allodynic Therapeutics is pioneering a non-opioid approach to treating neuropathic pain and migraine with its naltrexone-acetaminophen combination. The company has generated promising data from four investigator-initiated Phase 2 trials and is advancing into a formal Phase 2 study for acute migraine. By targeting the Toll-Like Receptor 4 (TLR4) and COX-2 pathways, the combination aims to address a significant unmet need in pain management, potentially offering a safer alternative to opioids and tapping into a large market of millions of patients in the U.S.

View full company profile

About Allodynic Therapeutics

Allodynic Therapeutics is pioneering a non-opioid approach to treating neuropathic pain and migraine with its naltrexone-acetaminophen combination. The company has generated promising data from four investigator-initiated Phase 2 trials and is advancing into a formal Phase 2 study for acute migraine. By targeting the Toll-Like Receptor 4 (TLR4) and COX-2 pathways, the combination aims to address a significant unmet need in pain management, potentially offering a safer alternative to opioids and tapping into a large market of millions of patients in the U.S.

View full company profile

About Allodynic Therapeutics

Allodynic Therapeutics is pioneering a non-opioid approach to treating neuropathic pain and migraine with its naltrexone-acetaminophen combination. The company has generated promising data from four investigator-initiated Phase 2 trials and is advancing into a formal Phase 2 study for acute migraine. By targeting the Toll-Like Receptor 4 (TLR4) and COX-2 pathways, the combination aims to address a significant unmet need in pain management, potentially offering a safer alternative to opioids and tapping into a large market of millions of patients in the U.S.

View full company profile

Other Acute Migraine Drugs

DrugCompanyPhase
PUR3100PulmatrixPhase 2
TRV250TrevenaPhase 1
ELYXYB®SCILEXMarketed
Elyxyb® (celecoxib oral solution)Scilex HoldingCommercial