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MYD88 Epigenetic Repressor

Hemophagocytic lymphohistiocytosis (HLH)

Pre-clinicalActive

Key Facts

Indication
Hemophagocytic lymphohistiocytosis (HLH)
Phase
Pre-clinical
Status
Active
Company

About GenexGen

GenexGen is a private, preclinical-stage biotech based in Cambridge, USA, founded in 2016. The company has pivoted from its initial gene therapy focus to a novel epigenetic platform using mRNA to deliver repressors that can durably silence key immune drivers like MYD88. This approach aims to create the first targeted therapy for the rare, fatal disease HLH, while establishing a platform with potential applications in broader inflammatory and age-related conditions. The company is backed by a mix of venture capital, foundation, and government grants.

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Other Hemophagocytic lymphohistiocytosis (HLH) Drugs

DrugCompanyPhase
Mini-CAR for HLHCaravan BiologixPre-clinical