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MRT-8102

IL-1β/NLRP3 driven Inflammatory Diseases

Phase 1ActiveNCT07119125

Key Facts

Indication
IL-1β/NLRP3 driven Inflammatory Diseases
Phase
Phase 1
Status
Active
Company

About Monte Rosa Therapeutics

Monte Rosa Therapeutics is on a mission to redefine the druggable genome by developing precision molecular glue degraders (MGDs) that eliminate, rather than inhibit, pathogenic proteins. The company has rapidly advanced from its 2018 founding to a public entity with multiple clinical-stage assets, underscored by a landmark $2.1B+ partnership with Novartis for its lead immunology candidate, MRT-6160. Its strategy centers on leveraging the proprietary QuEEN™ discovery engine—integrating AI, structural biology, and proteomics—to systematically target novel protein surfaces and build a broad pipeline across high-value therapeutic areas.

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Other IL-1β/NLRP3 driven Inflammatory Diseases Drugs

DrugCompanyPhase
Next Generation (NEK7)Monte Rosa TherapeuticsPreclinical