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LB-100 + Dostarlimab

Ovarian Clear Cell Carcinoma (OCCC)

Phase 2ActiveNCT06065462

Key Facts

Indication
Ovarian Clear Cell Carcinoma (OCCC)
Phase
Phase 2
Status
Active
Company

About Lixte Biotechnology

Lixte Biotechnology is a clinical-stage company focused on developing novel small molecule PP2A inhibitors to enhance existing cancer treatments. Its core achievement is the advancement of its lead asset, LB-100, into Phase 1b and Phase 2 trials in combination with chemotherapy and immunotherapy for indications like ovarian clear cell carcinoma and metastatic colon cancer. The company's strategy leverages a lean operational model to generate clinical proof-of-concept data that can attract partnership interest, given the broad potential of its platform to sensitize tumors to standard-of-care regimens. Lixte is publicly traded but operates as a micro-cap entity, reflecting its early-stage, high-risk/high-reward profile.

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About Lixte Biotechnology

Lixte Biotechnology is a clinical-stage company focused on developing novel small molecule PP2A inhibitors to enhance existing cancer treatments. Its core achievement is the advancement of its lead asset, LB-100, into Phase 1b and Phase 2 trials in combination with chemotherapy and immunotherapy for indications like ovarian clear cell carcinoma and metastatic colon cancer. The company's strategy leverages a lean operational model to generate clinical proof-of-concept data that can attract partnership interest, given the broad potential of its platform to sensitize tumors to standard-of-care regimens. Lixte is publicly traded but operates as a micro-cap entity, reflecting its early-stage, high-risk/high-reward profile.

View full company profile

Therapeutic Areas