Lasofoxifene
ER+, HER2-negative, ESR1-mutated metastatic breast cancer
Phase 3Active - ELAINE-3 trial ongoing
Key Facts
Indication
ER+, HER2-negative, ESR1-mutated metastatic breast cancer
Phase
Phase 3
Status
Active - ELAINE-3 trial ongoing
Company
About LeonaBio
LeonaBio is dedicated to developing novel therapeutics for devastating diseases with limited treatment options, focusing on oncology and neurology. The company's strategy leverages two distinct, late-stage small molecule candidates: lasofoxifene for treatment-resistant metastatic breast cancer and ATH-1105 for ALS. Following a significant financing and licensing deal for lasofoxifene in late 2025, LeonaBio is advancing its Phase 3 ELAINE-3 trial while building a pipeline of earlier-stage compounds. The company is led by an experienced management team with deep expertise in biotech development and finance.
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