K-554
Metabolic Disorders / Obesity
PreclinicalActive
Key Facts
About Kallyope
Kallyope is a private, clinical-stage biotech translating groundbreaking neuroscience into novel therapeutics for migraine and metabolic diseases. Its lead asset, elismetrep (K-304), is a first-in-class TRPM8 antagonist for migraine entering pivotal studies in 2026, supported by positive Phase 2b data. The company's proprietary Klarity™ platform identifies novel neural circuits, fueling a pipeline that includes a differentiated non-incretin metabolic candidate (K-554) and a discovery partnership with Novo Nordisk. With a seasoned leadership team and backing from top-tier life science investors, Kallyope aims to address large markets with significant unmet need.
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