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Isunakinra

Microsatellite Stable, KRAS-mutated Colorectal Cancer

Phase 2AActive

Key Facts

Indication
Microsatellite Stable, KRAS-mutated Colorectal Cancer
Phase
Phase 2A
Status
Active
Company

About Buzzard Pharmaceutical

Buzzard Pharmaceuticals is a Swedish biotech advancing isunakinra, a potent dual IL-1α/IL-1β inhibitor, for cancer. The company is building on promising Phase I data and is currently running a Phase 2A study in microsatellite stable, KRAS-mutated colorectal cancer, with plans to initiate a trial in neoadjuvant triple-negative breast cancer. Its strategy leverages the role of IL-1 as a master regulator of tumor-promoting inflammation and immunosuppression, aiming to enhance the efficacy of existing immunotherapies like PD-1 inhibitors.

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About Buzzard Pharmaceutical

Buzzard Pharmaceuticals is a Swedish biotech advancing isunakinra, a potent dual IL-1α/IL-1β inhibitor, for cancer. The company is building on promising Phase I data and is currently running a Phase 2A study in microsatellite stable, KRAS-mutated colorectal cancer, with plans to initiate a trial in neoadjuvant triple-negative breast cancer. Its strategy leverages the role of IL-1 as a master regulator of tumor-promoting inflammation and immunosuppression, aiming to enhance the efficacy of existing immunotherapies like PD-1 inhibitors.

View full company profile

Therapeutic Areas