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Ibezapolstat (ACX-362E)

Clostridioides difficile Infection (CDI)

Phase 2bActive, EnrollingNCT06183133

Key Facts

Indication
Clostridioides difficile Infection (CDI)
Phase
Phase 2b
Status
Active, Enrolling
Company

About Acurx Pharmaceuticals

Acurx Pharmaceuticals is a publicly traded, clinical-stage biotech focused on developing DNA polymerase IIIC inhibitors, a new class of antibiotics for Gram-positive bacterial infections deemed urgent threats. Its primary achievement is advancing its lead candidate, ibezapolstat, into a Phase 2b trial for CDI, with promising early clinical data. The company's strategy is to leverage its focused platform and experienced leadership to achieve regulatory approval for ibezapolstat, potentially under expedited pathways, while exploring the broader utility of its mechanism against other resistant pathogens like MRSA and VRE.

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C. difficile DiagnosticsTechLabCommercial
BioPYM Platform (Lead Program)FzataPre-clinical