Hypertension Program
Hypertension
Key Facts
About Closed Loop Medicine
Closed Loop Medicine is a clinical-stage digital therapeutics company pioneering a platform that integrates AI-driven, adaptive drug dosing with companion digital software. Its core strategy involves partnering with pharmaceutical companies to develop and commercialize personalized, combination prescription products, with an initial commercial and clinical focus on GLP-1 therapies for obesity and related conditions. The company has launched its first product in the U.S., secured key patents, and is actively building a pipeline in other chronic disease areas like hypertension and insomnia. It operates as a private, venture-backed firm leveraging regulatory designations for its software as a medical device.
View full company profileAbout Current Surgical
Current Surgical is a private, pre-revenue medical device startup founded in 2016, building a foundational platform for the next generation of minimally invasive, digital surgery. Its core technology integrates AI-processed real-time imaging with precision focused ultrasound ablation in a closed-loop control system, initially targeting early-stage solid tumor ablation. The company has a clear multi-year pipeline to expand into cardiac, pain, and neurological markets, is backed by elite investors like True Ventures, and has secured non-dilutive funding from the NIH and NSF to advance its platform.
View full company profileOther Hypertension Drugs
| Drug | Company | Phase |
|---|---|---|
| ALN-AGT01 | Alnylam Pharmaceuticals | Phase 1 |
| Norvasc | Viatris | Approved |
| Asomex | Mankind Pharma | Commercial |
| Oxemia | Zydus Lifesciences | Approved |
| Next-generation aldosterone synthase inhibitors | Mineralys Therapeutics | Preclinical |
| Losartan | Granules India | Approved/Commercial |
| Norliqva® (Amlodipine Oral Solution) | CMP Pharma | Approved |
| DehydraTECH-CBD for Hypertension | Lexaria Bioscience | Phase 1b/2a |
| Renal & Hepatic Denervation for Hypertension | Metavention | Feasibility |
| MVD-1 (SANA) | Eolo Pharma | Discovery |
| Peregrine System Renal Denervation | Ablative Solutions | Phase 3 |
| GMRx2 | George Medicines | Phase 3 |