Home/Pipeline/GLY-200

GLY-200

Obesity

Phase 2Active

Key Facts

Indication

Obesity

Phase

Phase 2

Status

Active

Company

Glyscend Therapeutics

About Glyscend Therapeutics

Glyscend Therapeutics is pioneering a novel, non-invasive approach to treating metabolic diseases by orally administering polymers that form a temporary coating in the duodenum, mimicking the duodenal exclusion mechanism of gastric bypass surgery. The company's lead candidate, GLY-200, is in Phase 2 trials for obesity, with potential applications in type 2 diabetes and NAFLD/NASH. Backed by venture capital and led by a team with deep experience in metabolic drug development, Glyscend aims to offer a safe, effective, and accessible alternative to invasive surgical procedures for a massive global patient population.

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Therapeutic Areas

Metabolic Gastrointestinal

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LET003	Harbour BioMed	Discovery	Active (Global)
LET001	Harbour BioMed	Discovery	Active (Global)
RGT-075	Regor Therapeutics	Phase 2b	Active
Anti‑Obesity Oral Drug	Premas Biotech	Phase 1	Active
Obesity Target Discovery Collaboration	Fauna Bio	Target Discovery/Preclinical	Active
GLP-1 variants	Heligenics	Discovery	Active
MYO Platform (Metabolic Disease)	Renbio	Pre-clinical	Active
Obesity Clinical Trials	IMA Clinical Research	Not Applicable (Service)	Active
KAYO-2000	KayoThera	Preclinical	Active
MVD-1 (SANA)	Eolo Pharma	Phase 1	Active
GIP-neutralizing antibody	Helicore Biopharma	Pre-clinical	Active
Antral Gastroplasty / Endoscopic Sleeve	Endo-TAGSS	Pre-clinical	Active