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GABA-A PAM for Essential Tremor

Essential Tremor

PreclinicalActive

Key Facts

Indication

Essential Tremor

Phase

Preclinical

Status

Active

Company

Modulate Bio

About Modulate Bio

Modulate Bio is a private, pre-revenue biotech founded in 2021, leveraging a proprietary platform to design selective GABA-A PAMs for neurological disorders. The company is nearing a development candidate for Essential Tremor, its lead program, with a pipeline that includes epilepsy and anxiety. Backed by academic roots from Harvard and Brigham and Women's Hospital, the team combines deep drug discovery expertise with a clear focus on validated targets with significant unmet medical need.

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Therapeutic Areas

Neurology Psychiatry

Other Essential Tremor Drugs

Drug	Company	Phase	Status
SAGE-324	Sage Therapeutics	Phase 2	Active
Platform Expansion	Rune Labs	Research	Active
Exablate Neuro	Insightec	Approved	Active
Felix NeuroAI™ Wristband	Fasikl	Approved	Active
Ulixacaltamide (PRAX-944)	Praxis Precision Medicines	Phase 3	Active