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Evorpacept + Trastuzumab + Ramucirumab + Paclitaxel (ASPEN-06)

2L/3L Advanced HER2+ Gastric/GEJ Adenocarcinoma

Phase 2/3Active, not recruiting

Key Facts

Indication
2L/3L Advanced HER2+ Gastric/GEJ Adenocarcinoma
Phase
Phase 2/3
Status
Active, not recruiting
Company

About ALX Oncology

ALX Oncology is a clinical-stage biotech focused on developing evorpacept, a next-generation CD47 inhibitor engineered to minimize toxicity while promoting macrophage-mediated tumor destruction. The company's core strategy is to develop evorpacept as a synergistic backbone therapy in combination with established and emerging oncology agents, with multiple Phase 2 trials underway. Key achievements include establishing proof-of-concept in gastric cancer and securing strategic collaborations with major pharmaceutical partners to expand its clinical reach.

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Therapeutic Areas