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Etakafusp alfa (AB248)

Recurrent locally advanced or metastatic solid tumors (Melanoma, RCC, NSCLC, SCCHN)

Phase 1a/1bActive, dose escalation and expansionNCT05653882

Key Facts

Indication
Recurrent locally advanced or metastatic solid tumors (Melanoma, RCC, NSCLC, SCCHN)
Phase
Phase 1a/1b
Status
Active, dose escalation and expansion
Company

About Asher Biotherapeutics

Asher Bio is developing a new generation of immunotherapies using its proprietary cis-targeting platform, which aims to solve the fundamental challenge of selectivity by engaging both an immunomodulatory receptor and a specific surface marker on the same target cell. The company's lead program, etakafusp alfa, has demonstrated proof of mechanism and early anti-tumor activity in an ongoing Phase 1a/1b trial, validating the platform. With a pipeline extending into infectious diseases and a focus on strategic collaborations, Asher Bio is positioned to expand the therapeutic potential of immunomodulators across multiple indications.

View full company profile

About Asher Biotherapeutics

Asher Bio is developing a new generation of immunotherapies using its proprietary cis-targeting platform, which aims to solve the fundamental challenge of selectivity by engaging both an immunomodulatory receptor and a specific surface marker on the same target cell. The company's lead program, etakafusp alfa, has demonstrated proof of mechanism and early anti-tumor activity in an ongoing Phase 1a/1b trial, validating the platform. With a pipeline extending into infectious diseases and a focus on strategic collaborations, Asher Bio is positioned to expand the therapeutic potential of immunomodulators across multiple indications.

View full company profile

About Asher Biotherapeutics

Asher Bio is developing a new generation of immunotherapies using its proprietary cis-targeting platform, which aims to solve the fundamental challenge of selectivity by engaging both an immunomodulatory receptor and a specific surface marker on the same target cell. The company's lead program, etakafusp alfa, has demonstrated proof of mechanism and early anti-tumor activity in an ongoing Phase 1a/1b trial, validating the platform. With a pipeline extending into infectious diseases and a focus on strategic collaborations, Asher Bio is positioned to expand the therapeutic potential of immunomodulators across multiple indications.

View full company profile