EP547

Cholestatic Pruritus

Phase 2Active

Key Facts

Indication
Cholestatic Pruritus
Phase
Phase 2
Status
Active
Company

About Escient Pharmaceuticals

Escient Pharmaceuticals is a San Diego-based biotech pioneering the development of oral MRGPR antagonists to treat neurosensory-inflammatory disorders. Its lead clinical candidates are EP262, an MRGPRX2 antagonist for mast cell-mediated diseases like chronic urticaria, and EP547, an MRGPRX4 antagonist for cholestatic pruritus. Founded in 2017, the company was acquired by Incyte in May 2024, providing significant resources to advance its novel pipeline. Escient's approach targets the interface between the neurosensory and immune systems, aiming to create differentiated treatments for underserved patient populations.

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Other Cholestatic Pruritus Drugs

DrugCompanyPhase
Cholestatic Pruritus TrialScience 37Phase 2