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Elismetrep (K-304)

Acute Treatment of Migraine

Phase 2Active

Key Facts

Indication
Acute Treatment of Migraine
Phase
Phase 2
Status
Active
Company

About Kallyope

Kallyope is a private, clinical-stage biotech translating groundbreaking neuroscience into novel therapeutics for migraine and metabolic diseases. Its lead asset, elismetrep (K-304), is a first-in-class TRPM8 antagonist for migraine entering pivotal studies in 2026, supported by positive Phase 2b data. The company's proprietary Klarity™ platform identifies novel neural circuits, fueling a pipeline that includes a differentiated non-incretin metabolic candidate (K-554) and a discovery partnership with Novo Nordisk. With a seasoned leadership team and backing from top-tier life science investors, Kallyope aims to address large markets with significant unmet need.

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