EB103

Relapsed/Refractory B-cell Non-Hodgkin Lymphoma (NHL)

Phase I/IIRecruitingSTARLIGHT-1 (NCT not on site)

Key Facts

Indication
Relapsed/Refractory B-cell Non-Hodgkin Lymphoma (NHL)
Phase
Phase I/II
Status
Recruiting
Company

About Estrella Immunopharma

Estrella Immunopharma's mission is to extend the curative power of T-cell therapies to a broader range of cancers and autoimmune diseases by addressing the critical limitations of current CAR-T products. The company has achieved an 83% overall response rate in a proof-of-concept study for B-cell lymphoma with its lead ARTEMIS candidate, EB103, and reported no severe CRS. Its strategy involves first advancing its CD19-targeted programs in hematologic malignancies, then leveraging a unique oncolytic virus-based 'mark-and-kill' platform to tackle the vast solid tumor market, while also exploring applications in autoimmune conditions like lupus.

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Other Relapsed/Refractory B-cell Non-Hodgkin Lymphoma (NHL) Drugs

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Obecabtagene autoleucel (obe-cel)Autolus TherapeuticsPhase 1
CRG-023CARGO TherapeuticsPreclinical